|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001339,
umls-concept:C0008633,
umls-concept:C0030705,
umls-concept:C0033684,
umls-concept:C0179400,
umls-concept:C0205082,
umls-concept:C0229671,
umls-concept:C0441889,
umls-concept:C0442805,
umls-concept:C0750502,
umls-concept:C1257890
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2006-11-2
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|
pubmed:abstractText |
Multiple organ failure because of systemic inflammatory response in the early phase and sepsis in the late phase is the main contributor to high mortality in severe acute pancreatitis (SAP). High-mobility group box chromosomal protein 1 (HMGB1) was recently identified as a potent proinflammatory mediator and increases in various pathological conditions such as sepsis. The aim of this study was to investigate contributions of HMGB1 in SAP.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1536-4828
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
33
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
359-63
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pubmed:meshHeading |
pubmed-meshheading:17079940-Bacterial Infections,
pubmed-meshheading:17079940-Bilirubin,
pubmed-meshheading:17079940-Biological Markers,
pubmed-meshheading:17079940-C-Reactive Protein,
pubmed-meshheading:17079940-Female,
pubmed-meshheading:17079940-HMGB1 Protein,
pubmed-meshheading:17079940-Humans,
pubmed-meshheading:17079940-L-Lactate Dehydrogenase,
pubmed-meshheading:17079940-Male,
pubmed-meshheading:17079940-Middle Aged,
pubmed-meshheading:17079940-Multiple Organ Failure,
pubmed-meshheading:17079940-Pancreatitis,
pubmed-meshheading:17079940-Pancreatitis, Acute Necrotizing,
pubmed-meshheading:17079940-Prognosis,
pubmed-meshheading:17079940-Severity of Illness Index,
pubmed-meshheading:17079940-Systemic Inflammatory Response Syndrome,
pubmed-meshheading:17079940-Time Factors
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|
pubmed:year |
2006
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|
pubmed:articleTitle |
Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis.
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pubmed:affiliation |
Department of Gastroenterological Surgery, Kobe University Graduate School of Medical Sciences, Japan. yasudatk@med.kobe-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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