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pubmed-article:17079354pubmed:abstractTextThe epidermal growth factor receptor (EGFR) has been reported to be overexpressed in anaplastic thyroid carcinoma (ATC). In vitro studies have shown that EGFR tyrosine kinase inhibitors (TKIs) greatly inhibit cellular growth and induced apoptosis in the ATC cell lines, while somatic mutations in the tyrosine kinase domain or an increased gene copy number are associated with increased sensitivity to TKIs in non-small cell lung cancer.lld:pubmed
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pubmed-article:17079354pubmed:articleTitleEpidermal growth factor receptor status in anaplastic thyroid carcinoma.lld:pubmed
pubmed-article:17079354pubmed:affiliationResearch Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, Korea.lld:pubmed
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