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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0031437,
umls-concept:C0043157,
umls-concept:C0205214,
umls-concept:C0220938,
umls-concept:C0311400,
umls-concept:C0681850,
umls-concept:C1414052,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1882417,
umls-concept:C2349001,
umls-concept:C2603343,
umls-concept:C2697811
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pubmed:issue |
1
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pubmed:dateCreated |
2007-1-8
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pubmed:abstractText |
The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been reported to associate with insulin resistance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
363-6
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pubmed:meshHeading |
pubmed-meshheading:17077128-Adult,
pubmed-meshheading:17077128-Cohort Studies,
pubmed-meshheading:17077128-Diabetes Mellitus, Type 2,
pubmed-meshheading:17077128-European Continental Ancestry Group,
pubmed-meshheading:17077128-Female,
pubmed-meshheading:17077128-Humans,
pubmed-meshheading:17077128-Insulin Resistance,
pubmed-meshheading:17077128-Iodide Peroxidase,
pubmed-meshheading:17077128-Male,
pubmed-meshheading:17077128-Middle Aged,
pubmed-meshheading:17077128-Obesity,
pubmed-meshheading:17077128-Phenotype,
pubmed-meshheading:17077128-Polymorphism, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.
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pubmed:affiliation |
Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark. ngrp@steno.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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