rdf:type |
|
lifeskim:mentions |
umls-concept:C0007613,
umls-concept:C0011306,
umls-concept:C0012694,
umls-concept:C0026809,
umls-concept:C0103647,
umls-concept:C0205314,
umls-concept:C0221239,
umls-concept:C0679622,
umls-concept:C1292733,
umls-concept:C1527148,
umls-concept:C1721442
|
pubmed:issue |
11
|
pubmed:dateCreated |
2006-12-4
|
pubmed:abstractText |
NK026680 is a newly identified type of immunosuppressive agent that inhibits dendritic cell (DC) functions and consequently reduces the mortality of mice with experimental acute graft-versus-host disease. This study was undertaken to evaluate NK026680 suppression of DC functions in preventing development of rapidly progressive glomerulonephritis (RPGN) and perinuclear antineutrophil cytoplasmic antibodies (pANCA) in SCG/Kj mice.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3707-15
|
pubmed:meshHeading |
pubmed-meshheading:17075885-Animals,
pubmed-meshheading:17075885-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:17075885-Cytokines,
pubmed-meshheading:17075885-Dendritic Cells,
pubmed-meshheading:17075885-Glomerulonephritis,
pubmed-meshheading:17075885-Hematuria,
pubmed-meshheading:17075885-Immunosuppressive Agents,
pubmed-meshheading:17075885-Kidney,
pubmed-meshheading:17075885-Lymphatic Diseases,
pubmed-meshheading:17075885-Mice,
pubmed-meshheading:17075885-Mice, Inbred Strains,
pubmed-meshheading:17075885-Proteinuria,
pubmed-meshheading:17075885-Pyrimidines,
pubmed-meshheading:17075885-Survival Rate,
pubmed-meshheading:17075885-Triazoles
|
pubmed:year |
2006
|
pubmed:articleTitle |
NK026680, a novel suppressant of dendritic cell function, prevents the development of rapidly progressive glomerulonephritis and perinuclear antineutrophil cytoplasmic antibody in SCG/Kj mice.
|
pubmed:affiliation |
Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|