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rdf:type |
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lifeskim:mentions |
umls-concept:C0004096,
umls-concept:C0018591,
umls-concept:C0330390,
umls-concept:C0681850,
umls-concept:C0936012,
umls-concept:C1335671,
umls-concept:C1367657,
umls-concept:C1550501,
umls-concept:C1556094,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
2
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pubmed:dateCreated |
2006-10-31
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pubmed:abstractText |
The beta2-adrenergic receptor gene (ADRB2) is a target molecule of beta2-agonists. Single nucleotide polymorphisms (SNPs) in the ADRB2 are related to the effectiveness of beta2-agonists. However, there are some discrepancies in the results of pharmacogenetic studies of ADRB2 among different ethnic groups. The aims of this study were to determine the ADRB2 haplotypes and diplotypes in Japanese asthmatic and non-asthmatic subjects and to examine their relation to asthma and to compare these results with previous studies done in other ethnic groups.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1323-8930
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-8
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pubmed:dateRevised |
2008-3-6
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pubmed:meshHeading |
pubmed-meshheading:17075257-African Americans,
pubmed-meshheading:17075257-Asthma,
pubmed-meshheading:17075257-European Continental Ancestry Group,
pubmed-meshheading:17075257-Gene Frequency,
pubmed-meshheading:17075257-Genetic Predisposition to Disease,
pubmed-meshheading:17075257-Haplotypes,
pubmed-meshheading:17075257-Humans,
pubmed-meshheading:17075257-Japan,
pubmed-meshheading:17075257-Polymorphism, Single Nucleotide,
pubmed-meshheading:17075257-Receptors, Adrenergic, beta-2
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pubmed:year |
2006
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pubmed:articleTitle |
Molecular-based haplotype analysis of the beta 2-adrenergic receptor gene (ADRB2) in Japanese asthmatic and non-asthmatic subjects.
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pubmed:affiliation |
Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima City, Fukushima, Japan. munakata@fmu.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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