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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
31
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pubmed:dateCreated |
2006-10-31
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pubmed:abstractText |
In preclinical models, there is synergism between chemotherapy and recombinant human tumor necrosis factor (TNF) -related apoptosis-inducing ligand (TRAIL) on apoptosis induction in tumor cells. Therefore, the prognostic relevance was analyzed of the expression of TRAIL and its death receptors DR4 and DR5 on disease-free survival and overall survival in stage III colon cancer patients treated with adjuvant chemotherapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Regulatory Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, TNF-Related...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/TNF-Related Apoptosis-Inducing...,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF10A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF10B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TNFSF10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:Boersma-van EkWytskeW,
pubmed-author:BoezenH MarikeHM,
pubmed-author:HollemaHarryH,
pubmed-author:KleibeukerJan HJH,
pubmed-author:KoornstraJan JJJ,
pubmed-author:MulderNanno HNH,
pubmed-author:PlukkerJohn TJT,
pubmed-author:WestraJantine LJL,
pubmed-author:ZwartNynkeN,
pubmed-author:de JongStevenS,
pubmed-author:de VriesElisabeth GEG,
pubmed-author:van GeelenCaroline MCM
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4998-5004
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:17075118-Adult,
pubmed-meshheading:17075118-Aged,
pubmed-meshheading:17075118-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:17075118-Apoptosis,
pubmed-meshheading:17075118-Apoptosis Regulatory Proteins,
pubmed-meshheading:17075118-Chemotherapy, Adjuvant,
pubmed-meshheading:17075118-Colonic Neoplasms,
pubmed-meshheading:17075118-Disease-Free Survival,
pubmed-meshheading:17075118-Female,
pubmed-meshheading:17075118-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17075118-Humans,
pubmed-meshheading:17075118-Immunohistochemistry,
pubmed-meshheading:17075118-Male,
pubmed-meshheading:17075118-Membrane Glycoproteins,
pubmed-meshheading:17075118-Middle Aged,
pubmed-meshheading:17075118-Neoplasm Staging,
pubmed-meshheading:17075118-Odds Ratio,
pubmed-meshheading:17075118-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17075118-Predictive Value of Tests,
pubmed-meshheading:17075118-Prognosis,
pubmed-meshheading:17075118-Proportional Hazards Models,
pubmed-meshheading:17075118-Receptors, TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:17075118-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:17075118-Survival Analysis,
pubmed-meshheading:17075118-TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:17075118-Tumor Markers, Biological,
pubmed-meshheading:17075118-Tumor Necrosis Factor-alpha,
pubmed-meshheading:17075118-Up-Regulation
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pubmed:year |
2006
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pubmed:articleTitle |
Prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in adjuvantly treated stage III colon cancer patients.
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pubmed:affiliation |
Department of Medical Oncology, University Medical Center, University of Groningen, 9700 RB Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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