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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
4
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pubmed:dateCreated |
1975-12-28
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pubmed:abstractText |
Distribution of cytoplasmic vacuoles in purified T and B lymphocytes was analyzed in four cases of aspartylglucosaminuria (AGU) and in one case of neuronal ceroid lipofuscinosis (Spielmeyer-Sjörgren type). In all cases T cells were significantly more vacuolized than B cells. The ultrastructure of the cytoplasmic vacuoles was consistent with the concept of storage lysosomes. The cytoplasmic vacuoles both in T and B cells similar to abnormal lysosomes seen in the visceral organs in these diseases.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Sep
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pubmed:issn |
0340-6075
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
11
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|
pubmed:volume |
18
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
263-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:170734-Adolescent,
pubmed-meshheading:170734-Adult,
pubmed-meshheading:170734-Aspartylglucosaminuria,
pubmed-meshheading:170734-B-Lymphocytes,
pubmed-meshheading:170734-Female,
pubmed-meshheading:170734-Humans,
pubmed-meshheading:170734-Inclusion Bodies,
pubmed-meshheading:170734-Intellectual Disability,
pubmed-meshheading:170734-Lipid Metabolism, Inborn Errors,
pubmed-meshheading:170734-Lipofuscin,
pubmed-meshheading:170734-Lymphocytes,
pubmed-meshheading:170734-Lysosomes,
pubmed-meshheading:170734-Male,
pubmed-meshheading:170734-Metabolism, Inborn Errors,
pubmed-meshheading:170734-T-Lymphocytes,
pubmed-meshheading:170734-Vacuoles
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pubmed:year |
1975
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|
pubmed:articleTitle |
Distribution of cytoplasmic vacuoles in blood T and B lymphocytes in two lysosomal disorders.
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pubmed:publicationType |
Journal Article
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