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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-11-7
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pubmed:abstractText |
The cycle of gallbladder filling and emptying controls the flow of bile into the intestine for digestion. Here we show that fibroblast growth factor-15, a hormone made by the distal small intestine in response to bile acids, is required for gallbladder filling. These studies demonstrate that gallbladder filling is actively regulated by an endocrine pathway and suggest a postprandial timing mechanism that controls gallbladder motility.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-8956
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pubmed:author |
pubmed-author:BinghamS FSF,
pubmed-author:BookoutAngie LAL,
pubmed-author:ChoiMihwaM,
pubmed-author:GerardRobert DRD,
pubmed-author:HolmstromSam RSR,
pubmed-author:KliewerSteven ASA,
pubmed-author:LiPengP,
pubmed-author:MangelsdorfDavid JDJ,
pubmed-author:MoschettaAntonioA,
pubmed-author:RichardsonJames AJA,
pubmed-author:UmetaniMichihisaM,
pubmed-author:XuH EricHE
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1253-5
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17072310-Animals,
pubmed-meshheading:17072310-Cholecystokinin,
pubmed-meshheading:17072310-Cyclic AMP,
pubmed-meshheading:17072310-Cyclic GMP,
pubmed-meshheading:17072310-Female,
pubmed-meshheading:17072310-Fibroblast Growth Factors,
pubmed-meshheading:17072310-Gallbladder,
pubmed-meshheading:17072310-Mice,
pubmed-meshheading:17072310-Mice, Knockout,
pubmed-meshheading:17072310-Polymerase Chain Reaction,
pubmed-meshheading:17072310-RNA, Messenger
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pubmed:year |
2006
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pubmed:articleTitle |
Identification of a hormonal basis for gallbladder filling.
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pubmed:affiliation |
Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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