Source:http://linkedlifedata.com/resource/pubmed/id/17071284
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9546
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pubmed:dateCreated |
2006-10-30
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pubmed:abstractText |
The optimum treatment choice between initial highly-active antiretroviral therapy (HAART) with a protease inhibitor (PI) versus a non-nucleoside reverse transcriptase inhibitor (NNRTI) is uncertain. An indirect analysis reported that PI-based HAART was better than NNRTI-based HAART. However, direct evidence for competing interventions is deemed more reliable than indirect evidence for making treatment decisions. We did a meta-analysis of head-to-head trials and compared the results with those of indirect analyses.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1474-547X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
368
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1503-15
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17071284-Adult,
pubmed-meshheading:17071284-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:17071284-Female,
pubmed-meshheading:17071284-HIV Infections,
pubmed-meshheading:17071284-HIV Protease Inhibitors,
pubmed-meshheading:17071284-Humans,
pubmed-meshheading:17071284-Male,
pubmed-meshheading:17071284-Randomized Controlled Trials as Topic,
pubmed-meshheading:17071284-Reverse Transcriptase Inhibitors
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pubmed:year |
2006
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pubmed:articleTitle |
Initial highly-active antiretroviral therapy with a protease inhibitor versus a non-nucleoside reverse transcriptase inhibitor: discrepancies between direct and indirect meta-analyses.
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pubmed:affiliation |
Oregon Evidence-based Practice Center, Oregon Health and Science University, Portland, OR 97239, USA. chour@ohsu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Meta-Analysis
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