rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1991-5-6
|
pubmed:abstractText |
The kinetics of antibody response to the group determinant a and subdeterminants d and y of hepatitis B virus were studied after infection and following immunisation with two recombinant DNA yeast-derived hepatitis B vaccines. The initial antibody response was to the subdeterminant epitopes, whereas anti-a antibody, which provides protection against different subtypes of the virus, was not detected for some weeks or months. The delay in the development of anti-a antibody after active immunisation raises important issues of early protection against infection.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0146-6615
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
219-24
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1707087-Adolescent,
pubmed-meshheading:1707087-Adult,
pubmed-meshheading:1707087-Aged,
pubmed-meshheading:1707087-Epitopes,
pubmed-meshheading:1707087-Female,
pubmed-meshheading:1707087-Hepatitis B,
pubmed-meshheading:1707087-Hepatitis B Antibodies,
pubmed-meshheading:1707087-Hepatitis B Surface Antigens,
pubmed-meshheading:1707087-Hepatitis B virus,
pubmed-meshheading:1707087-Humans,
pubmed-meshheading:1707087-Italy,
pubmed-meshheading:1707087-Kinetics,
pubmed-meshheading:1707087-Middle Aged,
pubmed-meshheading:1707087-Vaccines, Synthetic,
pubmed-meshheading:1707087-Viral Vaccines
|
pubmed:year |
1990
|
pubmed:articleTitle |
Kinetics of antibody response to hepatitis B virus determinants and to recombinant vaccines in Italy.
|
pubmed:affiliation |
Institute of Virology, University of Milan, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|