Source:http://linkedlifedata.com/resource/pubmed/id/17065799
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-10-26
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pubmed:abstractText |
Comparative studies among four species--Akodonazarae (2n = 38), A. lindberghi (2n = 42), A. paranaensis (2n = 44) and A. serrensis (2n = 46)--employing classic cytogenetics (C- and G-bands) and fluorescence in situ hybridization with telomeric (TTAGGG)n sequencesare reported here. Non-telomeric signals in addition to the regular telomeric sites were detected in three species:A. azarae, A. lindberghi and A. serrensis. One interstitial telomeric site (ITS) was observed proximally at the long arm of chromosome 1 of A. azarae. The comparison of G-banding patterns among the species indicated that the ITS was due to a tandem fusion/fission rearrangement. Non-telomeric signals of A. lindberghi and A. serrensis were not related to chromosomal rearrangements; instead, the sequences co-localized with (i) heterochromatic regions of all chromosomes in A. serrensis; (ii) some heterochromatic regions in A. lindberghi, and (iii) both euchromatic and heterochromatic regions in the metacentric pair of A. lindberghi. These exceptional findings revealed that ITS in Akodon can be related to chromosomal rearrangements and repetitive sequences in the constitutive heterochromatin and that the richness of TTAGGG-like sequences in the euchromatin could be hypothesized to be a result of amplification of the referred sequence along the chromosome arms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1424-859X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2006 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
169-75
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17065799-Animals,
pubmed-meshheading:17065799-Biological Evolution,
pubmed-meshheading:17065799-Brazil,
pubmed-meshheading:17065799-Chromosomes,
pubmed-meshheading:17065799-Euchromatin,
pubmed-meshheading:17065799-Heterochromatin,
pubmed-meshheading:17065799-In Situ Hybridization, Fluorescence,
pubmed-meshheading:17065799-Karyotyping,
pubmed-meshheading:17065799-Muridae,
pubmed-meshheading:17065799-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:17065799-Species Specificity,
pubmed-meshheading:17065799-Telomere
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pubmed:year |
2006
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pubmed:articleTitle |
Non-telomeric sites as evidence of chromosomal rearrangement and repetitive (TTAGGG)n arrays in heterochromatic and euchromatic regions in four species of Akodon (Rodentia, Muridae).
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pubmed:affiliation |
Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo Laboratório de Genética, São Paulo, Brazil. kabiousp@yahoo.com.br
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pubmed:publicationType |
Journal Article,
Comparative Study
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