Source:http://linkedlifedata.com/resource/pubmed/id/17064908
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2006-11-20
|
pubmed:abstractText |
beta-d-Glucosyl-O-l-tyrosine (1) is a humoral factor that stimulates transcription of the acyl-CoA binding protein (ACBP) in the pheromone gland of the Silkmoth, Bombyx mori. This paper describes stereoselective synthesis of five analogs that changed the sugar and/or amino acid part in 1 and their stimulatory activities on the ACBP transcription in the pheromone gland of B. mori. Among the analogs tested, beta-d-galactosyl-O-l-tyrosine showed a 1/5 potency compared to the activity of 1.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0968-0896
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
97-103
|
pubmed:meshHeading |
pubmed-meshheading:17064908-Animals,
pubmed-meshheading:17064908-Biological Assay,
pubmed-meshheading:17064908-Bombyx,
pubmed-meshheading:17064908-Diazepam Binding Inhibitor,
pubmed-meshheading:17064908-Female,
pubmed-meshheading:17064908-Gene Expression Regulation,
pubmed-meshheading:17064908-Molecular Conformation,
pubmed-meshheading:17064908-Monosaccharides,
pubmed-meshheading:17064908-Pupa,
pubmed-meshheading:17064908-Stereoisomerism,
pubmed-meshheading:17064908-Structure-Activity Relationship,
pubmed-meshheading:17064908-Tyrosine
|
pubmed:year |
2007
|
pubmed:articleTitle |
Synthesis and biological activities of analogs of D-glucosyl-l-tyrosine, a humoral factor that stimulates transcription of the acyl-CoA binding protein in the pheromone gland of the Silkmoth, Bombyx mori.
|
pubmed:affiliation |
RIKEN (The Institute of Physical and Chemical Research), Wako-shi, Saitama 351-0198, Japan. shunyat@riken.go.jp
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|