Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
26
pubmed:dateCreated
2006-11-7
pubmed:abstractText
Gastric acid production is important in intestinal iron absorption. The peptide hormone gastrin exists in both amidated and non-amidated forms, which stimulate and potentiate gastric acid secretion, respectively. Since non-amidated gastrins require ferric ions for biological activity in vitro, this study investigated the connection between iron status and gastrin by measurement of circulating gastrin concentrations in mice and humans with hemochromatosis. Gastrin concentrations are increased in the plasma and gastric mucosa of Hfe(-/-) mice, and in the sera of humans with HFE-related hemochromatosis. The discovery of a relationship between iron status and circulating gastrin concentrations opens a new perspective on the mechanisms of iron homeostasis.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-10207163, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-1064897, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-10756356, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-10953028, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-11181951, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-11535048, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-11745407, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-11781287, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-12270941, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-12529348, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-12606179, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-12737947, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-12787741, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-13634342, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-14530269, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-15128280, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-15238241, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-15514116, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-16407589, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-16476869, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-1974721, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-2007356, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-5681025, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-7286584, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-8772521, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-9287997, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-9352860, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-9482913, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-9679032, http://linkedlifedata.com/resource/pubmed/commentcorrection/17064691-9692706
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
580
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6195-8
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Circulating gastrin is increased in hemochromatosis.
pubmed:affiliation
University of Melbourne Department of Surgery, Austin Health, Level 8, Lance Townsend Building, Studley Road, Heidelberg, Vic. 3084, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural