Source:http://linkedlifedata.com/resource/pubmed/id/17064059
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
|
pubmed:dateCreated |
2006-10-26
|
pubmed:abstractText |
[3 + 2]-Cycloadditions of alkyl azides with various unsymmetrical internal alkynes in the presence of CpRuCl(PPh3)2 as catalyst in refluxing benzene have been examined, leading to 1,4,5-trisubstituted-1,2,3-triazoles. Whereas alkyl phenyl and dialkyl acetylenes undergo cycloadditions to afford mixtures of regioisomeric 1,2,3-triazoles, acyl-substituted internal alkynes react with complete regioselectivity. In addition, propargyl alcohols and propargyl amines were found to react with azides to afford single regioisomeric products.
|
pubmed:grant | |
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064059-11975567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064059-15330631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064059-15631470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064059-15816729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17064059-16287266
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0022-3263
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
27
|
pubmed:volume |
71
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
8680-3
|
pubmed:dateRevised |
2010-9-15
|
pubmed:meshHeading | |
pubmed:year |
2006
|
pubmed:articleTitle |
A study of the scope and regioselectivity of the ruthenium-catalyzed [3 + 2]-cycloaddition of azides with internal alkynes.
|
pubmed:affiliation |
Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|