|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001779,
umls-concept:C0017337,
umls-concept:C0035647,
umls-concept:C0043157,
umls-concept:C0043210,
umls-concept:C0086860,
umls-concept:C0220938,
umls-concept:C0332281,
umls-concept:C0439234,
umls-concept:C0907532,
umls-concept:C1336076,
umls-concept:C1518424,
umls-concept:C1882417
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|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2006-10-30
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|
pubmed:abstractText |
Nitric oxide (NO) is constitutively synthesized in the endothelium by endothelial nitric oxide synthase (eNOS) and acts as a pleiotropic regulator involved in carcinogenesis. Most breast cancers develop from mammary epithelial cells; therefore, NO may play a role in their development. It was hypothesized that eNOS polymorphisms are associated with risk of breast cancer.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0008-543X
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pubmed:author |
|
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pubmed:copyrightInfo |
(c) 2006 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
107
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2245-53
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17063466-Adult,
pubmed-meshheading:17063466-Breast Neoplasms,
pubmed-meshheading:17063466-Carcinoma,
pubmed-meshheading:17063466-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:17063466-Endothelium,
pubmed-meshheading:17063466-European Continental Ancestry Group,
pubmed-meshheading:17063466-Female,
pubmed-meshheading:17063466-Humans,
pubmed-meshheading:17063466-Middle Aged,
pubmed-meshheading:17063466-Nitric Oxide Synthase Type III,
pubmed-meshheading:17063466-Polymorphism, Genetic,
pubmed-meshheading:17063466-Promoter Regions, Genetic,
pubmed-meshheading:17063466-Questionnaires,
pubmed-meshheading:17063466-Reference Values,
pubmed-meshheading:17063466-Risk Factors
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pubmed:year |
2006
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|
pubmed:articleTitle |
Promoter polymorphism (-786t>C) in the endothelial nitric oxide synthase gene is associated with risk of sporadic breast cancer in non-Hispanic white women age younger than 55 years.
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pubmed:affiliation |
Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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