Source:http://linkedlifedata.com/resource/pubmed/id/17062670
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20 Pt 1
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pubmed:dateCreated |
2006-10-25
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pubmed:abstractText |
Induction of molecular chaperone Grp78 (78-kDa glucose-regulated protein) occurs in stress conditions that often characterize tumor microenvironments. We investigated the role of Grp78 in prostate cancer progression and the development of castration resistance, where cancer cells continue to survive despite the stress of an androgen-starved environment.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5987-93
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17062670-Cohort Studies,
pubmed-meshheading:17062670-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17062670-Heat-Shock Proteins,
pubmed-meshheading:17062670-Humans,
pubmed-meshheading:17062670-Male,
pubmed-meshheading:17062670-Molecular Chaperones,
pubmed-meshheading:17062670-Neoplasm Staging,
pubmed-meshheading:17062670-Orchiectomy,
pubmed-meshheading:17062670-Prostatic Neoplasms,
pubmed-meshheading:17062670-Stress, Physiological,
pubmed-meshheading:17062670-Tumor Cells, Cultured
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pubmed:year |
2006
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pubmed:articleTitle |
Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer.
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pubmed:affiliation |
Department of Pathology, University of Southern California, Keck School of Medicine/USC Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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