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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20 Pt 1
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pubmed:dateCreated |
2006-10-25
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pubmed:abstractText |
The growth-related oncogene alpha (GROalpha) is a secreted interleukin-like molecule that interacts with the CXCR2 G-protein-coupled receptor. We found that the mRNA and protein products of GROalpha are more highly expressed in neoplastic than normal colon epithelium, and we studied potential mechanisms by which GROalpha may contribute to tumor initiation or growth.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CXCL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL1,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/fibulin
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AmentaPeter SPS,
pubmed-author:BacolodManny DMD,
pubmed-author:BaranyFrancisF,
pubmed-author:GálI SIS,
pubmed-author:GeraldWilliamW,
pubmed-author:GiardinaSarah FSF,
pubmed-author:GreenmanJenniferJ,
pubmed-author:HammingDavidD,
pubmed-author:NottermanDanielD,
pubmed-author:PatyPhillipP,
pubmed-author:ShiaJinruJ,
pubmed-author:WenYuY,
pubmed-author:ZachariahEmmanuelE
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5951-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17062666-3T3 Cells,
pubmed-meshheading:17062666-Adenocarcinoma,
pubmed-meshheading:17062666-Animals,
pubmed-meshheading:17062666-Calcium-Binding Proteins,
pubmed-meshheading:17062666-Cell Line, Tumor,
pubmed-meshheading:17062666-Cell Survival,
pubmed-meshheading:17062666-Chemokine CXCL1,
pubmed-meshheading:17062666-Chemokines, CXC,
pubmed-meshheading:17062666-Colonic Neoplasms,
pubmed-meshheading:17062666-DNA, Neoplasm,
pubmed-meshheading:17062666-Gene Expression Profiling,
pubmed-meshheading:17062666-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17062666-Humans,
pubmed-meshheading:17062666-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:17062666-Mice,
pubmed-meshheading:17062666-Neoplasm Transplantation,
pubmed-meshheading:17062666-Polymerase Chain Reaction,
pubmed-meshheading:17062666-RNA, Messenger,
pubmed-meshheading:17062666-RNA, Neoplasm,
pubmed-meshheading:17062666-Transplantation, Heterologous
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pubmed:year |
2006
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pubmed:articleTitle |
GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1.
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pubmed:affiliation |
Robert Wood Johnson Medical School and Cancer Institute of New Jersey, New Brunswick, New Jersey 08903, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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