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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-11-20
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pubmed:abstractText |
Mesenteric lymph may provide the mechanistic link between gut ischemia and acute lung injury after hemorrhagic shock (HS). Studies have focused on the toxic mediators that develop in the post-shock mesenteric lymph (PSML). However, a complementary possibility is that there is loss of protective mediators found in pre-shock normal mesenteric lymph (NML) after HS. We hypothesize that NML protects against inflammatory insults to the pulmonary endothelium and that this effect is lost in PSML.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-71
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17059833-Albumins,
pubmed-meshheading:17059833-Animals,
pubmed-meshheading:17059833-Cells, Cultured,
pubmed-meshheading:17059833-Cholesterol,
pubmed-meshheading:17059833-Endothelial Cells,
pubmed-meshheading:17059833-Endotoxemia,
pubmed-meshheading:17059833-Humans,
pubmed-meshheading:17059833-Intercellular Adhesion Molecule-1,
pubmed-meshheading:17059833-Ischemia,
pubmed-meshheading:17059833-Lipopolysaccharides,
pubmed-meshheading:17059833-Lipoproteins,
pubmed-meshheading:17059833-Lymphatic System,
pubmed-meshheading:17059833-Male,
pubmed-meshheading:17059833-Mesentery,
pubmed-meshheading:17059833-Neutrophils,
pubmed-meshheading:17059833-Pneumonia,
pubmed-meshheading:17059833-Rats,
pubmed-meshheading:17059833-Rats, Sprague-Dawley,
pubmed-meshheading:17059833-Shock, Hemorrhagic,
pubmed-meshheading:17059833-Triglycerides
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pubmed:year |
2006
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pubmed:articleTitle |
Normal mesenteric lymph blunts the pulmonary inflammatory response to endotoxin.
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pubmed:affiliation |
Department of Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, Denver, Colorado 80204, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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