Source:http://linkedlifedata.com/resource/pubmed/id/17059578
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2006-10-24
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pubmed:abstractText |
Targeting protective gene expression to porcine endothelium has obvious advantages in xenotransplantation, but no endothelial cell-specific promoters have yet been used successfully in transgenic pigs. We have previously reported that a human intercellular adhesion molecule-2 (ICAM-2) gene promoter fragment functioned efficiently in transgenic mice but not pigs, suggesting that it lacked important transcriptional signals. In this study, we cloned and characterized regulatory elements of the pig ICAM-2 gene.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0908-665X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
514-21
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17059578-Animals,
pubmed-meshheading:17059578-Base Sequence,
pubmed-meshheading:17059578-Cell Adhesion Molecules,
pubmed-meshheading:17059578-Cell Line,
pubmed-meshheading:17059578-Cercopithecus aethiops,
pubmed-meshheading:17059578-Endothelial Cells,
pubmed-meshheading:17059578-Humans,
pubmed-meshheading:17059578-Introns,
pubmed-meshheading:17059578-Molecular Sequence Data,
pubmed-meshheading:17059578-Mutation,
pubmed-meshheading:17059578-Promoter Regions, Genetic,
pubmed-meshheading:17059578-Swine,
pubmed-meshheading:17059578-Transgenes
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pubmed:year |
2006
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pubmed:articleTitle |
Towards endothelial cell-specific transgene expression in pigs: characterization of the pig ICAM-2 promoter.
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pubmed:affiliation |
Immunology Research Centre, St Vincent's Health, Fitzroy, Victoria, Australia.
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pubmed:publicationType |
Journal Article
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