Linked Life Data

17057945

Source:http://linkedlifedata.com/resource/pubmed/id/17057945

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-4-3
pubmed:abstractText
The nervous system may be involved in up to 30% of patients with Sjogren's syndrome (SS). We describe three patients with Sjogren's syndrome and a concomitant parkinsonian syndrome. Elevated titers of anti-beta2-glycoprotein I IgG were found in the serum of all three patients. This autoantibody is strongly associated with anticardiolipin (aCL) antibodies, antiphospholipid syndrome (APS), and thromboembolic phenomena, but its role in the pathogenesis of the parkinsonian disorder in SS is unclear. These patients may present a subtype of SS patients in which the presence of aCL antibodies is associated with central nervous system involvement predominantly in the basal ganglia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0770-3198
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
743-7
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Anti-beta2-glycoprotein I in Sjogren's syndrome is associated with parkinsonism.
pubmed:affiliation
Department of Neurology, Sackler Faculty of Medicine, Chaim Sheba Medical Center, Tel Aviv University, Tel-Hashomer 52621, Tel-Aviv, Israel.
pubmed:publicationType
Journal Article, Case Reports