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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-10-23
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pubmed:abstractText |
The protein tyrosine phosphatase (PTP) superfamily of enzymes functions in a coordinated manner with protein tyrosine kinases to control signalling pathways that underlie a broad spectrum of fundamental physiological processes. In this review, I describe recent breakthroughs in our understanding of the role of the PTPs in the regulation of signal transduction and the aetiology of human disease.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1471-0072
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
833-46
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:17057753-Binding Sites,
pubmed-meshheading:17057753-Gene Expression Regulation,
pubmed-meshheading:17057753-Humans,
pubmed-meshheading:17057753-Ligands,
pubmed-meshheading:17057753-Models, Biological,
pubmed-meshheading:17057753-Neoplasms,
pubmed-meshheading:17057753-Oxidation-Reduction,
pubmed-meshheading:17057753-Protein Tyrosine Phosphatases,
pubmed-meshheading:17057753-Signal Transduction,
pubmed-meshheading:17057753-Structure-Activity Relationship,
pubmed-meshheading:17057753-Tumor Suppressor Proteins,
pubmed-meshheading:17057753-Tyrosine
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pubmed:year |
2006
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pubmed:articleTitle |
Protein tyrosine phosphatases: from genes, to function, to disease.
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pubmed:affiliation |
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA. tonks@cshl.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural
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