Source:http://linkedlifedata.com/resource/pubmed/id/17056958
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-10-23
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pubmed:abstractText |
In a prospective observational study of 1038 adult admissions to a 31-bed medical/surgical intensive care unit (ICU), acute respiratory failure (ARF, defined as a Pao(2)/Fio(2) ratio <or=200 mm Hg and the need for respiratory support) occurred in 182 (58%) of the 313 admissions with an ICU stay of more than 48 h. Initial ARF (onset within 48 h of ICU admission) occurred in 133 (42%) patients, and delayed onset ARF (onset >48 h after ICU admission) in 49 (16%). On admission, the cardiovascular sequential organ failure assessment (SOFA) score was higher in initial than in delayed onset ARF (1.1 +/- 1.5 vs 0.6 +/- 1.2, P < 0.05). High admission serum C-reactive protein concentrations (OR 1.08, 95% CI 1.04-1.12, P = 0.0001) and SOFA scores (OR 1.20, 95% CI 1.08-1.33, P = 0.0007) were the factors independently associated with initial ARF, and a low Glasgow coma scale (GCS) score (OR 1.13, 95% CI 1.04-1.21, P = 0.0018) was associated with delayed onset ARF. In initial ARF, a high SOFA score (OR 1.24, 95% CI 1.12-1.38, P = 0.0001) and a low GCS score (OR 0.89, 95% CI 0.83-0.96, P = 0.0013) on admission, and in delayed onset ARF, a low GCS score at 48 h (OR 0.67, 95% CI 0.54-0.84, P = 0.0011) were independently associated with death. The mortality rate was similar for initial and delayed onset ARF.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1526-7598
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1219-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:17056958-Adult,
pubmed-meshheading:17056958-Aged,
pubmed-meshheading:17056958-Confidence Intervals,
pubmed-meshheading:17056958-Female,
pubmed-meshheading:17056958-Humans,
pubmed-meshheading:17056958-Male,
pubmed-meshheading:17056958-Middle Aged,
pubmed-meshheading:17056958-Odds Ratio,
pubmed-meshheading:17056958-Prospective Studies,
pubmed-meshheading:17056958-Respiratory Distress Syndrome, Adult,
pubmed-meshheading:17056958-Time Factors,
pubmed-meshheading:17056958-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Initial and delayed onset of acute respiratory failure: factors associated with development and outcome.
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pubmed:affiliation |
Department of Intensive Care Medicine, Erasme University Hospital, Route de Lennik 808, 1070 Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study
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