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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-11-20
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pubmed:abstractText |
Apoptotic cells have immunosuppressive activity, whereas necrotic cells activate immune response, indicating they might have different effects on immune rejection against splenic allografts. The aim of this study was to determine whether administration of apoptotic or necrotic splenocytes of donor origin could impact the acute rejection of splenic allografts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
247-54
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17056068-Acute Disease,
pubmed-meshheading:17056068-Animals,
pubmed-meshheading:17056068-Apoptosis,
pubmed-meshheading:17056068-Dose-Response Relationship, Radiation,
pubmed-meshheading:17056068-Graft Rejection,
pubmed-meshheading:17056068-Immune Tolerance,
pubmed-meshheading:17056068-Interferon-gamma,
pubmed-meshheading:17056068-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:17056068-Male,
pubmed-meshheading:17056068-Necrosis,
pubmed-meshheading:17056068-Rats,
pubmed-meshheading:17056068-Rats, Inbred WF,
pubmed-meshheading:17056068-Rats, Sprague-Dawley,
pubmed-meshheading:17056068-Spleen,
pubmed-meshheading:17056068-Transforming Growth Factor beta1,
pubmed-meshheading:17056068-Transplantation, Homologous
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pubmed:year |
2006
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pubmed:articleTitle |
Opposite effects of donor apoptotic versus necrotic splenocytes on splenic allograft tolerance.
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pubmed:affiliation |
Hepatosplenic Surgery Center of Heilongjiang Province/Department of General Surgery, First Clinical Medical School, Harbin Medical University, Harbin, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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