|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0030567,
umls-concept:C0040399,
umls-concept:C0047499,
umls-concept:C0058698,
umls-concept:C0255374,
umls-concept:C0332514,
umls-concept:C0348026,
umls-concept:C0949479,
umls-concept:C1522609,
umls-concept:C1554112,
umls-concept:C2603343
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pubmed:issue |
4
|
|
pubmed:dateCreated |
2007-3-15
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|
pubmed:abstractText |
Striatal postsynaptic D2 receptors in Parkinson's disease (PD) are thought to be upregulated in the first years of the disease, especially contralateral to the clinically most affected side. The aim of this study was to evaluate whether the highest striatal D2 binding is found contralateral to the most affected side in PD, and whether this upregulation can be used as a diagnostic tool.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1619-7070
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
502-7
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pubmed:meshHeading |
pubmed-meshheading:17053905-Benzamides,
pubmed-meshheading:17053905-Biological Markers,
pubmed-meshheading:17053905-Corpus Striatum,
pubmed-meshheading:17053905-Female,
pubmed-meshheading:17053905-Humans,
pubmed-meshheading:17053905-Male,
pubmed-meshheading:17053905-Middle Aged,
pubmed-meshheading:17053905-Parkinson Disease,
pubmed-meshheading:17053905-Pyrrolidines,
pubmed-meshheading:17053905-Radiopharmaceuticals,
pubmed-meshheading:17053905-Receptors, Dopamine D2,
pubmed-meshheading:17053905-Reproducibility of Results,
pubmed-meshheading:17053905-Sensitivity and Specificity,
pubmed-meshheading:17053905-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:17053905-Tropanes,
pubmed-meshheading:17053905-Up-Regulation
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Diagnostic value of asymmetric striatal D2 receptor upregulation in Parkinson's disease: an [123I]IBZM and [123I]FP-CIT SPECT study.
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|
pubmed:affiliation |
Department of Neurology (935), Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. C.Verstappen@neuro.umcn.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|
