Source:http://linkedlifedata.com/resource/pubmed/id/17051534
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-12-12
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pubmed:abstractText |
Post-transplant lymphoproliferative disorder (PTLD) is the most common treatment related malignancy that occurs after solid organ transplantation (SOT). PTLD has extended from its initial description as an Epstein-Barr virus (EBV)-driven B-cell proliferation to include EBV-negative and non B-lineage cases. T-cell PTLD (T-PTLD) is rare in both adults and children. We report two cases of pediatric T-PTLD after SOT (liver and lungs) and review cases reported in the literature. Both patients had a bimodal response to therapy with initial eradication of bulky nodal disease with regimens typically used to treat leukemia, but persistence of low-level clonal T-cells in marrow, CSF and lung in one case.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1545-5017
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2007 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
415-8
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pubmed:dateRevised |
2009-1-12
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pubmed:meshHeading |
pubmed-meshheading:17051534-Child, Preschool,
pubmed-meshheading:17051534-Female,
pubmed-meshheading:17051534-Humans,
pubmed-meshheading:17051534-Infant,
pubmed-meshheading:17051534-Liver Transplantation,
pubmed-meshheading:17051534-Lung Transplantation,
pubmed-meshheading:17051534-Lymphoproliferative Disorders,
pubmed-meshheading:17051534-T-Lymphocytes
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pubmed:year |
2008
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pubmed:articleTitle |
Pediatric T-cell post-transplant lymphoproliferative disorder after solid organ transplantation.
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pubmed:affiliation |
Departments of Pathology, Immunology, and Laboratory, University of Florida College of Medicine and the University of Florida Shands Cancer Center, Gainesville, Florida, USA. yfrank@hotmail.com
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pubmed:publicationType |
Journal Article,
Case Reports
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