Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-10-19
pubmed:abstractText
Little is known about the prevalence of dementia and its associated risk factors in developing countries. Some studies suggest that the prevalence of dementia is lower in developing countries than it is in high-income nations. We sought to determine risk factors for dementia in elderly persons in central Nigeria. Using the standardized Community Screening Instrument for Dementia, we screened a stratified, random community sample of 280 persons aged 65 years and older for dementia. We examined the independent association of known risk factors with dementia using logistic regression. The overall prevalence of dementia was 6.4% (95% CI 3.8-9.9%). Independent risk factors for dementia included female sex (OR 8.4; 95% CI 1.9-39), body mass index of 18.5 kg/m2 or less (OR 3.5; 95% CI 1.2-9.9), and age (OR 1.05 per year; 95% CI 1.00-1.11). Non-steroidal anti-inflammatory drug (NSAID) use was associated with a reduced risk of dementia (OR 0.20; 95% CI 0.04-0.93). Education, blood pressure, history of stroke, family history of dementia, and rural residence were not significantly associated with dementia in the multivariate model. The prevalence of dementia in central Nigeria may be greater than that found in other developing countries. Female sex, low body mass index, lack of NSAID use, and advancing age were the major risk factors in this population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1360-7863
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
616-20
pubmed:meshHeading
pubmed-meshheading:17050090-Age Factors, pubmed-meshheading:17050090-Aged, pubmed-meshheading:17050090-Aged, 80 and over, pubmed-meshheading:17050090-Body Mass Index, pubmed-meshheading:17050090-Cross-Sectional Studies, pubmed-meshheading:17050090-Dementia, pubmed-meshheading:17050090-Developing Countries, pubmed-meshheading:17050090-Educational Status, pubmed-meshheading:17050090-Female, pubmed-meshheading:17050090-Humans, pubmed-meshheading:17050090-Logistic Models, pubmed-meshheading:17050090-Male, pubmed-meshheading:17050090-Nigeria, pubmed-meshheading:17050090-Nutritional Status, pubmed-meshheading:17050090-Prevalence, pubmed-meshheading:17050090-Residence Characteristics, pubmed-meshheading:17050090-Risk Assessment, pubmed-meshheading:17050090-Risk Factors, pubmed-meshheading:17050090-Sex Factors
pubmed:year
2006
pubmed:articleTitle
Risk factors for dementia in central Nigeria.
pubmed:affiliation
Department of Family Medicine, Jos University Teaching Hospital, PMB 2076, Jos, Nigeria.
pubmed:publicationType
Journal Article