rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
1975-12-12
|
pubmed:abstractText |
This study was designed to assess the response of cyclic AMP to "endogenous" hormonal stimulation resulting from insulin-induced hypoglycemia. Insulin was administered to four normal subjects and four adrenalectomized patients. Hypoglycemia resulted in four-fold increases in plasma cyclic AMP. This response is thought to be secondary to beta-adrenergic stimulation for the following reasons: (1) the response was absent in adrenalectomized, cortisol-treated subjects; (2) it was abolished by propranolol; and (3) urinary excretion of cyclic AMP did not reflect the rise in plasma cyclic AMP.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0026-0495
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1139-44
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:170494-Adrenal Glands,
pubmed-meshheading:170494-Cyclic AMP,
pubmed-meshheading:170494-Epinephrine,
pubmed-meshheading:170494-Extracellular Space,
pubmed-meshheading:170494-Humans,
pubmed-meshheading:170494-Hypoglycemia,
pubmed-meshheading:170494-Insulin,
pubmed-meshheading:170494-Propranolol,
pubmed-meshheading:170494-Receptors, Adrenergic,
pubmed-meshheading:170494-Stimulation, Chemical
|
pubmed:year |
1975
|
pubmed:articleTitle |
Effect of hypoglycemia on extracellular levels of cyclic AMP in man.
|
pubmed:publicationType |
Journal Article
|