Linked Life Data

1704862

Source:http://linkedlifedata.com/resource/pubmed/id/1704862

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-3-27
pubmed:abstractText
The hsr-omega locus forms one of the largest Drosophila heat-shock puffs and produces three major transcripts. These three transcripts are also produced constitutively, at lower levels, in almost all tissues and developmental stages. The amounts of the transcripts in nonstressed cells are modulated during development. The hormone ecdysone leads to increased levels of hsr-omega transcripts in cultured cells, suggesting that changing ecdysone titers may play a role in the developmental changes of hsr-omega transcript levels. By in situ hybridization to RNA in tissue sections, we detect only two cell types that lack hsr-omega transcripts--the preblastoderm embryo and the primary spermatocyte. There are no maternal transcripts of hsr-omega in the embryo. Transcripts appear abruptly at the time that the zygotic genome becomes transcriptionally active, shortly before the formation of the cellular blastoderm. No constitutive hsr-omega transcripts are found in primary spermatocytes. The spermatocytes cannot respond to heat shock by transcribing either hsr-omega or hsp70 RNA. Constitutive hsr-omega transcription is resumed later in spermatogenesis and hsr-omega RNA is detected in differentiating spermatids. These spermatids are also capable of mounting a heat-shock response, as measured by increases in hsr-omega and hsp70 RNA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
144
pubmed:geneSymbol
hsr-omega
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-77
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Expression of heat-shock locus hsr-omega in nonstressed cells during development in Drosophila melanogaster.
pubmed:affiliation
Department of Biology, Queen's University, Kingston, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.