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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0007328,
umls-concept:C0085862,
umls-concept:C0600493,
umls-concept:C0750502,
umls-concept:C1299583,
umls-concept:C1418941,
umls-concept:C1549571,
umls-concept:C1556085,
umls-concept:C1608386,
umls-concept:C1852467,
umls-concept:C1882417
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pubmed:issue |
10
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pubmed:dateCreated |
2006-10-18
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pubmed:abstractText |
A single nucleotide polymorphism (SNP) in the coding region of the prion protein gene (PRNP) at codon 129 has been repeatedly shown to be an associated factor to sporadic Creutzfeldt-Jakob disease (sCJD), but additional major predisposing DNA variants for sCJD are still unknown. Several previous studies focused on the characterisation of polymorphisms in PRNP and the prion-like doppel gene (PRND), generating contradictory results on relatively small sample sets. Thus, extensive studies are required for validation of the polymorphisms in PRNP and PRND.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-10443888,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-10525406,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-10825657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-10987652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-10994001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11353827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11368906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11404459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11574147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11702213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-11704923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-12034503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-12145550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-14704188,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-14970845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-14976159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-15933804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-16032513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-16032514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-16042548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-1677164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-2574076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-7476138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-8666377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-8815857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-8878476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17047093-9811807
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1468-6244
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e53
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17047093-5' Untranslated Regions,
pubmed-meshheading:17047093-Case-Control Studies,
pubmed-meshheading:17047093-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:17047093-Female,
pubmed-meshheading:17047093-Gene Frequency,
pubmed-meshheading:17047093-Genetic Linkage,
pubmed-meshheading:17047093-Genetic Testing,
pubmed-meshheading:17047093-Genotype,
pubmed-meshheading:17047093-Germany,
pubmed-meshheading:17047093-Haplotypes,
pubmed-meshheading:17047093-Humans,
pubmed-meshheading:17047093-Linkage Disequilibrium,
pubmed-meshheading:17047093-Male,
pubmed-meshheading:17047093-Odds Ratio,
pubmed-meshheading:17047093-Polymorphism, Genetic,
pubmed-meshheading:17047093-Polymorphism, Single Nucleotide,
pubmed-meshheading:17047093-Prions,
pubmed-meshheading:17047093-Risk Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study.
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pubmed:publicationType |
Letter,
Comparative Study,
Research Support, Non-U.S. Gov't
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