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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9544
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pubmed:dateCreated |
2006-10-18
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pubmed:databankReference |
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pubmed:abstractText |
No effective therapeutic options for patients with unresectable imatinib-resistant gastrointestinal stromal tumour are available. We did a randomised, double-blind, placebo-controlled, multicentre, international trial to assess tolerability and anticancer efficacy of sunitinib, a multitargeted tyrosine kinase inhibitor, in patients with advanced gastrointestinal stromal tumour who were resistant to or intolerant of previous treatment with imatinib.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1474-547X
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pubmed:author |
pubmed-author:BaumCharles MCM,
pubmed-author:BelloCarlo LCL,
pubmed-author:BlacksteinMartin EME,
pubmed-author:CasaliPaolo GPG,
pubmed-author:DemetriGeorge DGD,
pubmed-author:DesaiJayeshJ,
pubmed-author:FletcherChristopher DCD,
pubmed-author:GarrettChristopher RCR,
pubmed-author:GeorgeSuzanneS,
pubmed-author:HeinrichMichael CMC,
pubmed-author:HuangXinX,
pubmed-author:JudsonIan RIR,
pubmed-author:McArthurGrantG,
pubmed-author:MorganJeffrey AJA,
pubmed-author:ShahManisha HMH,
pubmed-author:VerweijJaapJ,
pubmed-author:van OosteromAllan TAT
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
368
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1329-38
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pubmed:dateRevised |
2007-6-26
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pubmed:meshHeading |
pubmed-meshheading:17046465-Adult,
pubmed-meshheading:17046465-Aged,
pubmed-meshheading:17046465-Aged, 80 and over,
pubmed-meshheading:17046465-Antineoplastic Agents,
pubmed-meshheading:17046465-Double-Blind Method,
pubmed-meshheading:17046465-Female,
pubmed-meshheading:17046465-Gastrointestinal Stromal Tumors,
pubmed-meshheading:17046465-Humans,
pubmed-meshheading:17046465-Indoles,
pubmed-meshheading:17046465-Male,
pubmed-meshheading:17046465-Middle Aged,
pubmed-meshheading:17046465-Piperazines,
pubmed-meshheading:17046465-Protein Kinase Inhibitors,
pubmed-meshheading:17046465-Pyrimidines,
pubmed-meshheading:17046465-Pyrroles,
pubmed-meshheading:17046465-Survival Analysis,
pubmed-meshheading:17046465-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial.
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pubmed:affiliation |
Ludwig Center at Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. gdemetri@partners.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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