Linked Life Data

17044671

Source:http://linkedlifedata.com/resource/pubmed/id/17044671

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
42
pubmed:dateCreated
2006-10-18
pubmed:abstractText
One major drawback associated with single-walled carbon nanotubes (SWNTs) in the liquid phase is their hydrophobicity-induced aggregation, which prevents utilization of the unique physical and chemical properties of single SWNTs. Recently it has been found that lysophospholipids, or single-tailed phospholipids, can readily form supramolecular complexes with SWNTs and the resultant SWNT solubility is superior to that provided by nucleic acids, proteins, and surfactants such as sodium dodecyl sulfate. Using transmission electron microscopy, lysophospholipids were observed forming striations on SWNTs in a vacuum. Although the morphology of the striations seemingly favors the hemimicellular model, serious doubts remain about the arrangement of individual lipids within the striations. Here we present an in silico study of the binding of zwitterionic lysophosphatidylcholine to an SWNT. We present compelling evidence that the binding of lipid surfactants to cylindrical nanostructures in the liquid phase does not obey any of the three popular models in the literature. Understanding the binding of lipid amphiphiles to SWNTs facilitates the bottom-up design of novel nanostructures for supramolecular chemistry and nanotechnology and fuels new field studies of nanotoxicity and nanomedicine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-7863
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13656-7
pubmed:dateRevised
2008-1-17
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Lipid-carbon nanotube self-assembly in aqueous solution.
pubmed:affiliation
Laboratory of Single-Molecule Biophysics and Polymer Physics, Department of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't