Linked Life Data

17044382

Source:http://linkedlifedata.com/resource/pubmed/id/17044382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-10-18
pubmed:abstractText
Idiopathic hypereosinophilic syndrome (HES) is an uncommon condition characterized by an unexplained elevation of absolute eosinophil count (AEC) to > or = 1.5 x 10(9)/l for at least six months, and is frequently associated with eosinophil-mediated end organ damage. Idiopathic HES, as with secondary HES and primary hypereosinophilic clonal hematopoietic disorders, has a high incidence of myocardial, pulmonary, neurological and other organ injury. Myocardial fibroelastosis and valvular lesions are common, and successful treatment with valve replacement or resection of fibrotic myocardium has been reported. The case is described of a patient with idiopathic HES and multi-organ complications including severe mitral valve disease, in whom a functionally obstructive thrombosis of a newly inserted prosthetic mitral valve occurred despite adequate anticoagulation, when the AEC was profoundly elevated. Recurrent thrombosis has not occurred over a substantial period following AEC reduction with corticosteroids, and subsequent maintenance at normal levels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0966-8519
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Obstructive prosthetic mitral valve thrombosis in idiopathic hypereosinophilic syndrome: a case report and review of the literature.
pubmed:affiliation
St. Vincents Hospital Melbourne, Victoria, Australia. mickhii@hotmail.com
pubmed:publicationType
Journal Article, Review, Case Reports