rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2006-10-17
|
pubmed:abstractText |
A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1081-1206
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
97
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
321-8
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17042137-Adolescent,
pubmed-meshheading:17042137-Antigens, CD14,
pubmed-meshheading:17042137-Asthma,
pubmed-meshheading:17042137-Cells, Cultured,
pubmed-meshheading:17042137-Child,
pubmed-meshheading:17042137-Cytokines,
pubmed-meshheading:17042137-Endotoxins,
pubmed-meshheading:17042137-Female,
pubmed-meshheading:17042137-Genetic Predisposition to Disease,
pubmed-meshheading:17042137-Genotype,
pubmed-meshheading:17042137-Humans,
pubmed-meshheading:17042137-Leukocytes, Mononuclear,
pubmed-meshheading:17042137-Male,
pubmed-meshheading:17042137-Polymorphism, Genetic,
pubmed-meshheading:17042137-Promoter Regions, Genetic,
pubmed-meshheading:17042137-Reverse Transcriptase Polymerase Chain Reaction
|
pubmed:year |
2006
|
pubmed:articleTitle |
The effect of CD14-c159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children.
|
pubmed:affiliation |
Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|