Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-10-16
pubmed:abstractText
Calreticulin (CR) is a Ca(2+)-binding, multifunctional protein. The amazing array of CR-associated functions range from intracellular activities in secondary messenger release, protein folding and the modulation of gene expression to potential interactions with host receptors and signaling machinery and recognition by the host immune system. The multifunctional nature of CR may impact upon the ability of cells to recognize extracellular stimuli and coordinate appropriate responses. Identification of CR isolated from parasites and the conservation of its functions suggests that investigations into the contributions of CR to various aspects of parasite biology should be undertaken because it may reveal information regarding parasite interaction with the host and how the parasite may modulate its response to the host.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Apr
pubmed:issn
0169-4758
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
157-60
pubmed:year
1998
pubmed:articleTitle
Implications of calreticulin function in parasite biology.
pubmed:affiliation
Section on Viral Pathogenesis and Adverse Reactions, Division of Viral Products, OVRR, CBER, Food and Drug Administration, Bethesda, MD 20892, USA.
pubmed:publicationType
Journal Article