Source:http://linkedlifedata.com/resource/pubmed/id/17040495
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2006-10-16
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pubmed:abstractText |
Because poor skin wound healing associated with diabetes is thought to be partly a result from impaired angiogenesis, treatments that improve angiogenesis could have important clinical applications. We herein report the effects of novel developed material, collagen-poly glycolic acid fiber hybrid matrix, being used together with basic fibroblast growth factor to promote wound healing of full-thickness skin defects on the back of type 2 diabetic Lepr(db) mice. Our data indicates that this therapeutic approach markedly promotes angiogenesis and granulation tissue formation in comparison with other conditions 14 days after wounding.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0385-2407
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
670-5
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pubmed:meshHeading |
pubmed-meshheading:17040495-Animals,
pubmed-meshheading:17040495-Collagen,
pubmed-meshheading:17040495-Diabetes Mellitus, Type 2,
pubmed-meshheading:17040495-Fibroblast Growth Factor 2,
pubmed-meshheading:17040495-Granulation Tissue,
pubmed-meshheading:17040495-Mice,
pubmed-meshheading:17040495-Mice, Inbred C57BL,
pubmed-meshheading:17040495-Neovascularization, Physiologic,
pubmed-meshheading:17040495-Polyglycolic Acid,
pubmed-meshheading:17040495-Surgical Sponges,
pubmed-meshheading:17040495-Wound Healing,
pubmed-meshheading:17040495-Wounds, Penetrating
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pubmed:year |
2006
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pubmed:articleTitle |
Collagen-poly glycolic acid hybrid matrix with basic fibroblast growth factor accelerated angiogenesis and granulation tissue formation in diabetic mice.
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pubmed:affiliation |
Department of Dermatology and Plastic Surgery, Akita University School of Medicine, Hondo 1-1-1, Akita-shi, Akita 010-8543, Japan. naganaga@doc.med.akita-u.ac.jp
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pubmed:publicationType |
Journal Article
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