Source:http://linkedlifedata.com/resource/pubmed/id/17038899
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2006-10-13
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pubmed:abstractText |
Experimental therapeutics for degenerative and traumatic diseases of the nervous system have been recently enriched with the addition of neural stem cells (NSCs) as alternatives to fetal tissues for cell replacement. Neurodegenerative diseases present the additional problem that cell death signals may interfere with the viability of grafted cells. The adult spinal cord raises further challenges for NSC differentiation because of lack of intrinsic developmental potential and the negative outcomes of several prior attempts.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0041-1337
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
865-75
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17038899-Animals,
pubmed-meshheading:17038899-Animals, Genetically Modified,
pubmed-meshheading:17038899-Cell Differentiation,
pubmed-meshheading:17038899-Graft Survival,
pubmed-meshheading:17038899-Humans,
pubmed-meshheading:17038899-Male,
pubmed-meshheading:17038899-Motor Neuron Disease,
pubmed-meshheading:17038899-Neurons,
pubmed-meshheading:17038899-Polymorphism, Single Nucleotide,
pubmed-meshheading:17038899-Rats,
pubmed-meshheading:17038899-Shear Strength,
pubmed-meshheading:17038899-Spinal Cord,
pubmed-meshheading:17038899-Stem Cell Transplantation,
pubmed-meshheading:17038899-Transplantation, Heterologous
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pubmed:year |
2006
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pubmed:articleTitle |
Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats.
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pubmed:affiliation |
Department of Pathology, Division of Neuropathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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