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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-10-23
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pubmed:abstractText |
Mitochondrial DNA (mtDNA) haplotypes have become popular tools for tracing maternal ancestry, and several companies offer this service to the general public. Numerous studies have demonstrated that human mtDNA haplotypes can be used with confidence to identify the continent where the haplotype originated. Ideally, mtDNA haplotypes could also be used to identify a particular country or ethnic group from which the maternal ancestor emanated. However, the geographic distribution of mtDNA haplotypes is greatly influenced by the movement of both individuals and population groups. Consequently, common mtDNA haplotypes are shared among multiple ethnic groups. We have studied the distribution of mtDNA haplotypes among West African ethnic groups to determine how often mtDNA haplotypes can be used to reconnect Americans of African descent to a country or ethnic group of a maternal African ancestor. The nucleotide sequence of the mtDNA hypervariable segment I (HVS-I) usually provides sufficient information to assign a particular mtDNA to the proper haplogroup, and it contains most of the variation that is available to distinguish a particular mtDNA haplotype from closely related haplotypes. In this study, samples of general African-American and specific Gullah/Geechee HVS-I haplotypes were compared with two databases of HVS-I haplotypes from sub-Saharan Africa, and the incidence of perfect matches recorded for each sample.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-10090902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-10363131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-10581031,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-10739760,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-11806853,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-12015000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-12395296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-12646128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-14748829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-14970923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15225159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15226208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15248073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15340834,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15457403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15739384,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15761855,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15895434,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-15928903,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-16175514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-1840702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-7700157,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-8865992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-9326335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17038170-9543551
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1741-7007
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17038170-Africa, Western,
pubmed-meshheading:17038170-Africa South of the Sahara,
pubmed-meshheading:17038170-African Americans,
pubmed-meshheading:17038170-African Continental Ancestry Group,
pubmed-meshheading:17038170-DNA, Mitochondrial,
pubmed-meshheading:17038170-Databases, Genetic,
pubmed-meshheading:17038170-Haplotypes,
pubmed-meshheading:17038170-Humans,
pubmed-meshheading:17038170-Language
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pubmed:year |
2006
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pubmed:articleTitle |
African-American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups.
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pubmed:affiliation |
Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, 29208, USA. ely@sc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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