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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2006-10-12
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pubmed:abstractText |
From a structure-activity relationship perspective, the new indolocarbazoles 11 and 12 have been synthesized and evaluated biologically as novel Chk1 inhibitors. Compounds 11 and 12 were synthesized in high yield from indole via bisindolylmaleimides 18 and 24.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Sep
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|
pubmed:issn |
1477-0520
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
4
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
3228-34
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
|
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pubmed:year |
2006
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|
pubmed:articleTitle |
Synthesis of bisindolylmaleimides related to GF109203x and their efficient conversion to the bioactive indolocarbazoles.
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|
pubmed:affiliation |
Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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