rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2006-10-12
|
pubmed:abstractText |
The mutant 263-H9 with hypersensitivity to several stress conditions (1.5 mol/L Sorbitol, 0.65 mol/L NaCl and 15 degrees C) was obtained by using transposon mutagenesis in the Saccharomyces cerevisiae strain W303-1A. Unlike other mutants the transposon in 263-H9 was intergenic between GIP2 and YER053C-A. Using gene knockout, a yeast genomic library and other methods, the gene correlated with the salt stress response was identified. The data indicated that the phenotype of 263-H9 was not directly caused by the insertion of the transposon. On the other hand, the hypersensitivity to salt and other stress conditions was due to the deletion of 5 base pairs close to position 936 bp in the PBS2 gene essential for HOG signal pathway regulation under salt stress.
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pubmed:language |
chi
|
pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0253-9772
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
28
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1294-8
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17035190-DNA Transposable Elements,
pubmed-meshheading:17035190-Gene Library,
pubmed-meshheading:17035190-Genes, Fungal,
pubmed-meshheading:17035190-Mitogen-Activated Protein Kinase Kinases,
pubmed-meshheading:17035190-Mutation,
pubmed-meshheading:17035190-Phenotype,
pubmed-meshheading:17035190-Saccharomyces cerevisiae,
pubmed-meshheading:17035190-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:17035190-Sequence Deletion,
pubmed-meshheading:17035190-Sodium Chloride,
pubmed-meshheading:17035190-Stress, Physiological
|
pubmed:year |
2006
|
pubmed:articleTitle |
[Identification of the gene correlated with salt stress in the Saccharomyces cerevisiae 263-H9 mutant].
|
pubmed:affiliation |
State Key Laboratory of Microbial Technology, Shandong University, Ji'nan 250100, China. yudianking@163.com
|
pubmed:publicationType |
Journal Article,
English Abstract
|