rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-10-12
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pubmed:abstractText |
Lymphangioleiomyomatosis (LAM) is a rare destructive lung disease characterized by an abnormal proliferation of smooth muscle-like cells (LAM cells) in the lung and along the axial lymphatics. LAM demonstrates a heterogeneous clinical course, but there is no serum surrogate marker available for assessing the disease severity or predicting the disease progression. Since the authors have recently demonstrated the extensive LAM-associated lymphangiogenesis and its potential role in progression and metastasis of LAM cells, they hypothesized that serum levels of lymphangiogenic growth factors might be increased in LAM and become a surrogate marker for disease severity.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
1539-6851
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
143-52
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pubmed:dateRevised |
2007-5-2
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pubmed:meshHeading |
pubmed-meshheading:17034294-Adult,
pubmed-meshheading:17034294-Female,
pubmed-meshheading:17034294-Forced Expiratory Volume,
pubmed-meshheading:17034294-Hormones,
pubmed-meshheading:17034294-Humans,
pubmed-meshheading:17034294-Leiomyoma,
pubmed-meshheading:17034294-Lymphangioleiomyomatosis,
pubmed-meshheading:17034294-Middle Aged,
pubmed-meshheading:17034294-Myocytes, Smooth Muscle,
pubmed-meshheading:17034294-Respiratory Function Tests,
pubmed-meshheading:17034294-Uterine Neoplasms,
pubmed-meshheading:17034294-Vascular Endothelial Growth Factor A,
pubmed-meshheading:17034294-Vascular Endothelial Growth Factor C,
pubmed-meshheading:17034294-Vascular Endothelial Growth Factor D,
pubmed-meshheading:17034294-Vital Capacity
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pubmed:year |
2006
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pubmed:articleTitle |
Vascular endothelial growth factor-D is increased in serum of patients with lymphangioleiomyomatosis.
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pubmed:affiliation |
Department of Respiratory Medicine, Juntendo University, School of Medicine, and Pneumothorax Center, Nissan Tamagawa Hospital, Tokyo, Japan. kseyama@med.juntendo.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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