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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1991-2-25
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pubmed:abstractText |
Insulin-like growth factor binding proteins (IGF-BP) are secreted by several human small cell lung cancer cell lines (SCLC). In order to identify the IGF-BPs from SCLC cell lines the RNA from 10 different SCLC cell lines was analyzed by Northern blot analysis with the probes for three different IGF-BPs, IGFBP-1, IGFBP-2, and IGFBP-3. No hybridization signal could be detected with the probes encoding for IGFBP-1 and IGFBP-3. The hybridization with different IGFBP-2-specific oligodeoxynucleotide probes and with the corresponding full-length cDNA showed that all SCLC cell lines which secreted IGF-BPs express IGFBP-2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0014-4827
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
192
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
414-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1703084-Base Sequence,
pubmed-meshheading:1703084-Carcinoma, Small Cell,
pubmed-meshheading:1703084-Carrier Proteins,
pubmed-meshheading:1703084-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:1703084-Humans,
pubmed-meshheading:1703084-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:1703084-Lung Neoplasms,
pubmed-meshheading:1703084-Molecular Sequence Data,
pubmed-meshheading:1703084-Molecular Weight,
pubmed-meshheading:1703084-Neoplasm Proteins,
pubmed-meshheading:1703084-Poly A,
pubmed-meshheading:1703084-RNA, Messenger,
pubmed-meshheading:1703084-Tumor Cells, Cultured
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pubmed:year |
1991
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pubmed:articleTitle |
Insulin-like growth factor binding protein expression in human small cell lung cancer cell lines.
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pubmed:affiliation |
Philipps-University, Division of Hematology/Oncology, Marburg, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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