Source:http://linkedlifedata.com/resource/pubmed/id/17030084
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2007-1-15
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pubmed:abstractText |
How a developing embryo becomes "informed" about its form?" This problem remains obscure and controversial. We argue that the "information about a form" is distributed throughout three main components: the dynamic laws, the parameters and the initial/boundary conditions. In the absence of a dynamic law two other components are "blind", that is, do not contain any unambiguous information. We present a version of a dynamic law of morphogenesis, based upon the presumption of a feedback between passive and active mechanical stresses. We explore several models of shape formation based upon this law and show that, as depending upon the parameters values, they generate a large set of realistic shapes. Genetic and epigenetic basis of the models parameters is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0303-2647
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
204-14
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pubmed:meshHeading |
pubmed-meshheading:17030084-Animals,
pubmed-meshheading:17030084-Body Patterning,
pubmed-meshheading:17030084-Epigenesis, Genetic,
pubmed-meshheading:17030084-Feedback,
pubmed-meshheading:17030084-Hydrozoa,
pubmed-meshheading:17030084-Models, Biological,
pubmed-meshheading:17030084-Morphogenesis,
pubmed-meshheading:17030084-Stress, Mechanical,
pubmed-meshheading:17030084-Systems Biology
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pubmed:year |
2007
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pubmed:articleTitle |
Information about a form (on the dynamic laws of morphogenesis).
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pubmed:affiliation |
Department of Embryology, Faculty of Biology, Moscow State University, Moscow 119899, Russia. lbelous@soil.msu.ru
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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