Source:http://linkedlifedata.com/resource/pubmed/id/17030046
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2006-12-25
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| pubmed:abstractText |
The aim of the present study was to examine verb generation in a larger group of children and adolescents with acute focal lesions of the cerebellum. Nine children and adolescents with cerebellar tumours participated. Subjects were tested a few days after tumour surgery. For comparison, a subgroup was tested also 1 or 2 days before surgery. None of the children had received radiation or chemotherapy at or before the time of testing. Eleven age- and education-matched control subjects participated. Subjects had to generate verbs to blocked presentations of photographs of objects. As control condition, the objects had to be named. Furthermore, dysarthria was quantified by means of a sentence production and syllable repetition task. Detailed analysis of individual 3D-MR images revealed that lesions affected cerebellar hemispheres in all children and adolescents. The right cerebellar hemisphere was affected in four and the left hemisphere in five subjects. In the present study, naming and verb generation accuracy were preserved in the majority of subjects with cerebellar lesions. No significant signs of learning deficits were observed, as reduction of reaction times over blocks was not different compared to controls. There was a trend of children and adolescents with right-hemispheric lesions to perform worse compared to controls. In this group, however, significant signs of dysarthria were present. In sum, no significant signs of disordered verb generation were observed in children and adolescents with acute cerebellar lesions. Findings suggest that the role of the cerebellum in verb generation may be less pronounced than previously suggested. Findings need to be confirmed in a larger group of subjects with acute focal lesions.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Mar
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| pubmed:issn |
0028-3932
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
14
|
| pubmed:volume |
45
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
977-88
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| pubmed:dateRevised |
2009-11-11
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| pubmed:meshHeading |
pubmed-meshheading:17030046-Acute Disease,
pubmed-meshheading:17030046-Adolescent,
pubmed-meshheading:17030046-Adult,
pubmed-meshheading:17030046-Cerebellar Diseases,
pubmed-meshheading:17030046-Cerebellar Neoplasms,
pubmed-meshheading:17030046-Cerebellum,
pubmed-meshheading:17030046-Child,
pubmed-meshheading:17030046-Dysarthria,
pubmed-meshheading:17030046-Female,
pubmed-meshheading:17030046-Functional Laterality,
pubmed-meshheading:17030046-Humans,
pubmed-meshheading:17030046-Language Disorders,
pubmed-meshheading:17030046-Language Tests,
pubmed-meshheading:17030046-Male,
pubmed-meshheading:17030046-Matched-Pair Analysis,
pubmed-meshheading:17030046-Reaction Time,
pubmed-meshheading:17030046-Reference Values,
pubmed-meshheading:17030046-Verbal Behavior,
pubmed-meshheading:17030046-Verbal Learning,
pubmed-meshheading:17030046-Vocabulary
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| pubmed:year |
2007
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| pubmed:articleTitle |
Verb generation in children and adolescents with acute cerebellar lesions.
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| pubmed:affiliation |
Department of Neurology, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany. benedikt.frank@gmx.net
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|