|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2007-2-21
|
|
pubmed:abstractText |
Although insulin-like factor 3 (INSL3) and its receptor leucine-rich repeat-containing G protein-coupled receptor 8/G protein-coupled receptor affecting testis descent (LGR8/GREAT) are essential for the gubernacular development, mutations of INSL3 and LGR8/GREAT are infrequent in patients with cryptorchidism (CO), and there is no report documenting a positive association of CO with a polymorphism in INSL3 or LGR8/GREAT. Here, we further examined the relevance of INSL3 and LGR8/GREAT mutations and polymorphisms to the development of CO.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0301-0163
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright (c) 2007 S. Karger AG, Basel.
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
67
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
73-6
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:17028442-Adolescent,
pubmed-meshheading:17028442-Adult,
pubmed-meshheading:17028442-Child,
pubmed-meshheading:17028442-Child, Preschool,
pubmed-meshheading:17028442-Cryptorchidism,
pubmed-meshheading:17028442-Humans,
pubmed-meshheading:17028442-Infant,
pubmed-meshheading:17028442-Insulin,
pubmed-meshheading:17028442-Male,
pubmed-meshheading:17028442-Middle Aged,
pubmed-meshheading:17028442-Mutation,
pubmed-meshheading:17028442-Polymorphism, Genetic,
pubmed-meshheading:17028442-Proteins,
pubmed-meshheading:17028442-Receptors, G-Protein-Coupled
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Mutation and polymorphism analyses of INSL3 and LGR8/GREAT in 62 Japanese patients with cryptorchidism.
|
|
pubmed:affiliation |
Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, Tokyo, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
