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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-10-4
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pubmed:abstractText |
The sterol regulatory element-binding factor (SREBF)-1c is a transcription factor involved in the regulation of lipid and glucose metabolism. We have previously found evidence that a common SREBF1c single-nucleotide polymorphism (SNP), located between exons 18c and 19c, is associated with an increased risk of type 2 diabetes. The present study aimed to replicate our previously reported association in a larger case-control study and to examine an additional five SREBF1c SNPs for their association with diabetes risk and plasma glucose concentrations.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10207099,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10438539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10464332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10466767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10918064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-10934219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-11287605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-11334418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-11589378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-11916923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-11994399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-12048207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-12191470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-12193656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-14693662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-14748724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-14988272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-15277400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-15592482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-16005884,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-16255080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-7712700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-9062341,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-9356453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17019602-9421459
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0012-186X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2642-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17019602-Aged,
pubmed-meshheading:17019602-Blood Glucose,
pubmed-meshheading:17019602-Case-Control Studies,
pubmed-meshheading:17019602-Cohort Studies,
pubmed-meshheading:17019602-Diabetes Mellitus, Type 2,
pubmed-meshheading:17019602-Female,
pubmed-meshheading:17019602-Genotype,
pubmed-meshheading:17019602-Humans,
pubmed-meshheading:17019602-Male,
pubmed-meshheading:17019602-Middle Aged,
pubmed-meshheading:17019602-Polymorphism, Genetic,
pubmed-meshheading:17019602-Polymorphism, Single Nucleotide,
pubmed-meshheading:17019602-Sterol Regulatory Element Binding Protein 1
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pubmed:year |
2006
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pubmed:articleTitle |
Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.
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pubmed:affiliation |
MRC Epidemiology Unit, Cambridge, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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