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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-10-3
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pubmed:abstractText |
Tryptophan hydroxylase is the rate-limiting enzyme in the serotonin (5-HT) biosynthetic pathway responsible for the regulation of serotonin levels. Tryptophan hydroxylase 2 (TPH2) was found to be solely expressed in the brain and therefore considered an important susceptibility gene in psychiatric disorders.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-990X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1103-10
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17015812-Aged,
pubmed-meshheading:17015812-Bipolar Disorder,
pubmed-meshheading:17015812-Chromosomes, Human, Pair 12,
pubmed-meshheading:17015812-Depressive Disorder,
pubmed-meshheading:17015812-European Continental Ancestry Group,
pubmed-meshheading:17015812-Female,
pubmed-meshheading:17015812-Follow-Up Studies,
pubmed-meshheading:17015812-Gene Expression,
pubmed-meshheading:17015812-Genetic Markers,
pubmed-meshheading:17015812-Genetic Predisposition to Disease,
pubmed-meshheading:17015812-Genotype,
pubmed-meshheading:17015812-Haplotypes,
pubmed-meshheading:17015812-Humans,
pubmed-meshheading:17015812-Linkage Disequilibrium,
pubmed-meshheading:17015812-Male,
pubmed-meshheading:17015812-Middle Aged,
pubmed-meshheading:17015812-Molecular Sequence Data,
pubmed-meshheading:17015812-Polymorphism, Single Nucleotide,
pubmed-meshheading:17015812-Promoter Regions, Genetic,
pubmed-meshheading:17015812-Serotonin,
pubmed-meshheading:17015812-Sweden,
pubmed-meshheading:17015812-Tryptophan Hydroxylase
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pubmed:year |
2006
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pubmed:articleTitle |
Association of brain-specific tryptophan hydroxylase, TPH2, with unipolar and bipolar disorder in a Northern Swedish, isolated population.
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pubmed:affiliation |
Applied Molecular Genomics Group, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Antwerp, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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