rdf:type |
|
lifeskim:mentions |
umls-concept:C0012655,
umls-concept:C0021390,
umls-concept:C0332281,
umls-concept:C0439855,
umls-concept:C0441587,
umls-concept:C0441833,
umls-concept:C1442161,
umls-concept:C1707877,
umls-concept:C1826448,
umls-concept:C1882417,
umls-concept:C1999270
|
pubmed:issue |
10
|
pubmed:dateCreated |
2006-10-2
|
pubmed:abstractText |
Genetic association between inflammatory bowel disease (IBD) and NOD1 (CARD4) has recently been reported. This gene has structural similarity to NOD2 (CARD15), a confirmed susceptibility gene for Crohn"s disease (CD). The NOD1 association was strongest at novel complex indel ND1 + 32656. Our aim was to ascertain the contribution of ND1 + 32656 variants to IBD in a large independent United Kingdom dataset and to identify any subphenotype association within CD and ulcerative colitis (UC).
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1078-0998
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
967-71
|
pubmed:dateRevised |
2008-5-7
|
pubmed:meshHeading |
pubmed-meshheading:17012967-Adult,
pubmed-meshheading:17012967-Colitis, Ulcerative,
pubmed-meshheading:17012967-Crohn Disease,
pubmed-meshheading:17012967-Female,
pubmed-meshheading:17012967-Gene Deletion,
pubmed-meshheading:17012967-Gene Frequency,
pubmed-meshheading:17012967-Genetic Predisposition to Disease,
pubmed-meshheading:17012967-Genotype,
pubmed-meshheading:17012967-Great Britain,
pubmed-meshheading:17012967-Humans,
pubmed-meshheading:17012967-Inflammatory Bowel Diseases,
pubmed-meshheading:17012967-Male,
pubmed-meshheading:17012967-Middle Aged,
pubmed-meshheading:17012967-Mutagenesis, Insertional,
pubmed-meshheading:17012967-Nod1 Signaling Adaptor Protein,
pubmed-meshheading:17012967-Polymorphism, Genetic
|
pubmed:year |
2006
|
pubmed:articleTitle |
Complex insertion/deletion polymorphism in NOD1 (CARD4) is not associated with inflammatory bowel disease susceptibility in East Anglia panel.
|
pubmed:affiliation |
IBD Research Group, Addenbrooke's Hospital, University of Cambridge, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|