rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1991-1-15
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pubmed:abstractText |
Pretreatment of purified calf brain G proteins with activated pertussis toxin or antibodies raised against the C-terminus of their alpha subunits prevented the increase in GTPase activity induced by substance P, compound 48/80 and mastoparan. These results suggest that these mast cell secretagogues activate G proteins directly via an interaction with the C-terminus of alpha subunits of G proteins by mimicking the agonist-liganded receptors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/GTP Phosphohydrolases,
http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Pertussis Toxin,
http://linkedlifedata.com/resource/pubmed/chemical/Substance P,
http://linkedlifedata.com/resource/pubmed/chemical/Virulence Factors, Bordetella,
http://linkedlifedata.com/resource/pubmed/chemical/Wasp Venoms,
http://linkedlifedata.com/resource/pubmed/chemical/mastoparan,
http://linkedlifedata.com/resource/pubmed/chemical/p-Methoxy-N-methylphenethylamine
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0165-2478
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
355-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1701162-Amino Acid Sequence,
pubmed-meshheading:1701162-Animals,
pubmed-meshheading:1701162-Antibodies,
pubmed-meshheading:1701162-Cattle,
pubmed-meshheading:1701162-Enzyme Activation,
pubmed-meshheading:1701162-GTP Phosphohydrolases,
pubmed-meshheading:1701162-GTP-Binding Proteins,
pubmed-meshheading:1701162-Molecular Sequence Data,
pubmed-meshheading:1701162-Peptide Fragments,
pubmed-meshheading:1701162-Peptides,
pubmed-meshheading:1701162-Pertussis Toxin,
pubmed-meshheading:1701162-Protein Binding,
pubmed-meshheading:1701162-Substance P,
pubmed-meshheading:1701162-Virulence Factors, Bordetella,
pubmed-meshheading:1701162-Wasp Venoms,
pubmed-meshheading:1701162-p-Methoxy-N-methylphenethylamine
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pubmed:year |
1990
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pubmed:articleTitle |
Interaction of substance P, compound 48/80 and mastoparan with the alpha-subunit C-terminus of G protein.
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pubmed:affiliation |
Laboratoire de Neuroimmunopharmacologie, Université Louis Pasteur, Strasbourg I, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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