Linked Life Data

17009728

Source:http://linkedlifedata.com/resource/pubmed/id/17009728

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-10-2
pubmed:abstractText
Calreticulin (CRT) is an essential Ca2+-binding /storage chaperone resident protein of endoplasmic reticulum or sarcoplasmic reticulum found across a diverse range of species. The protein is involved in the regulation of intracellular Ca2+ homeostasis and endoplasmic reticulum Ca2+ storage capacity, and is also an important molecular chaperone involved in "quality control" within secretory pathways. Playing an important role in apoptosis, cell adhesion, gene expression and autoimmunity, calreticulin is involved in the genesis, development and prognosis of many diseases. Now we summarized the physiological function of CRT and its expression changes during myocardial hypertrophy, heart failure, angiogenesis, stresses and many other pathological conditions.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0559-7765
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
216-20
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Research on physiological and pathophysiological functions of calreticulin].
pubmed:affiliation
Department of Pathophysiology, Chinese PLA General Hospital, Beijing, China.
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't