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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-10-26
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pubmed:abstractText |
To investigate the effects of the recombinant immunotoxin dsFv anti-FRbeta-PE38, which consists of the disulfide-stabilized Fv fragment (dsFv) of the anti-folate receptor beta (anti-FRbeta) antibody and the 38-kd portion of Pseudomonas exotoxin A (PE38), on the activation and proliferation of cells that function in inflammatory and degradative processes in rheumatoid arthritis (RA) synovial tissue.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADP Ribose Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Toxins,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Disulfides,
http://linkedlifedata.com/resource/pubmed/chemical/Exotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Folate Receptors, GPI-Anchored,
http://linkedlifedata.com/resource/pubmed/chemical/Immunotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Virulence Factors,
http://linkedlifedata.com/resource/pubmed/chemical/toxA protein, Pseudomonas aeruginosa
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3126-34
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17009233-ADP Ribose Transferases,
pubmed-meshheading:17009233-Animals,
pubmed-meshheading:17009233-Antibodies,
pubmed-meshheading:17009233-Apoptosis,
pubmed-meshheading:17009233-Arthritis, Rheumatoid,
pubmed-meshheading:17009233-Bacterial Toxins,
pubmed-meshheading:17009233-Carrier Proteins,
pubmed-meshheading:17009233-Cell Line,
pubmed-meshheading:17009233-Cell Proliferation,
pubmed-meshheading:17009233-Disulfides,
pubmed-meshheading:17009233-Dose-Response Relationship, Drug,
pubmed-meshheading:17009233-Escherichia coli,
pubmed-meshheading:17009233-Exotoxins,
pubmed-meshheading:17009233-Folate Receptors, GPI-Anchored,
pubmed-meshheading:17009233-Humans,
pubmed-meshheading:17009233-Immunotoxins,
pubmed-meshheading:17009233-Liver,
pubmed-meshheading:17009233-Male,
pubmed-meshheading:17009233-Mice,
pubmed-meshheading:17009233-Mice, SCID,
pubmed-meshheading:17009233-Osteoclasts,
pubmed-meshheading:17009233-Receptors, Cell Surface,
pubmed-meshheading:17009233-Recombinant Proteins,
pubmed-meshheading:17009233-Synovial Membrane,
pubmed-meshheading:17009233-Transfection,
pubmed-meshheading:17009233-Virulence Factors
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pubmed:year |
2006
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pubmed:articleTitle |
In vitro and in vivo efficacy of a recombinant immunotoxin against folate receptor beta on the activation and proliferation of rheumatoid arthritis synovial cells.
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pubmed:affiliation |
Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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